Abubakar Abubakar

Recommended book of the weekend: 🍃 ☕ ➡️ "THE ATLAS OF LOVE" By Laurie Frankel 🍁🍁🍁🍁🍁🍁🍁🍁🍁🍁🍁🍁🍁🍁🍁🍁🍁🍁🍁🍁🍁🍁🍁🍁

“𝓣𝓱𝓮 𝓳𝓸𝔂𝓼 𝓸𝓯 𝓼𝓬𝓲𝓮𝓷𝓬𝓮 𝓵𝓲𝓮 𝓲𝓷 𝓽𝓱𝓮 𝓭𝓲𝓼𝓬𝓸𝓿𝓮𝓻𝔂.” - Rosalind Franklin 🧬 April 25 marks DNA Day, commemorating two defining milestones in modern medicine: the discovery of DNA’s double-helix structure & the completion of the Human Genome Project. Together, these achievements transformed genetics from theory into one of the most impactful sciences of our time.           🔹 In 1953, James Watson and Francis Crick, building on important data from Rosalind Franklin & Maurice Wilkins, proposed the double-helix model of DNA. The pairing of adenine-thymine & cytosine-guanine explained how hereditary information is stored, copied, & passed across generations. This discovery became the foundation of molecular biology, enabling recombinant DNA technology, genetic diagnostics, forensic science, & modern biotech.           🔹 Launched in 1990 & completed in...

Recommended book of the weekend: 🍃 ☕ ➡️ "THE GOD GENE" By Dean Hamer   🍁🍁🍁🍁🍁🍁🍁🍁🍁🍁🍁🍁🍁🍁🍁🍁🍁🍁🍁🍁🍁🍁🍁🍁

“𝓔𝓿𝓮𝓻𝔂 𝓹𝓸𝓹𝓾𝓵𝓪𝓽𝓲𝓸𝓷 𝓬𝓪𝓻𝓻𝓲𝓮𝓼 𝓪 𝓾𝓷𝓲𝓺𝓾𝓮 𝓬𝓱𝓪𝓹𝓽𝓮𝓻 𝓸𝓯 𝓽𝓱𝓮 𝓱𝓾𝓶𝓪𝓷 𝓼𝓽𝓸𝓻𝔂.” - Brenna Henn 🧬 Population genomics examines genome-wide variation across many individuals to understand ancestry, migration, adaptation, and disease biology. Unlike older methods focused on a few markers, modern genomics analyzes millions of variants simultaneously (linking evolution, medicine, and human history).           🔹 Human diversity reflects both unity and variation. All humans belong to one species and share around 99.9% of DNA, while the remaining variation contributes to traits such as pigmentation, lactose tolerance, immune responses, and other biological differences. These patterns emerged through migration, mutation, natural selection, and environmental interaction over time           🔹 Genomics has transformed our understanding of migration. Evidence strongly supports African origins for modern humans fol...

Recommended book of the weekend: 🍃 ☕ ➡️ "CHROMOSOME 6" By Robin Cook   🍁🍁🍁🍁🍁🍁🍁🍁🍁🍁🍁🍁🍁🍁🍁🍁🍁🍁🍁🍁🍁🍁🍁🍁

“𝓐𝓭𝓿𝓪𝓷𝓬𝓮𝓼 𝓲𝓷 𝓰𝓮𝓷𝓸𝓶𝓲𝓬𝓼 𝓪𝓻𝓮 𝓻𝓮𝓼𝓱𝓪𝓹𝓲𝓷𝓰 𝓱𝓸𝔀 𝔀𝓮 𝓮𝓿𝓪𝓵𝓾𝓪𝓽𝓮 𝓭𝓻𝓾𝓰 𝓼𝓪𝓯𝓮𝓽𝔂 𝓪𝓷𝓭 𝓮𝓯𝓯𝓮𝓬𝓽𝓲𝓿𝓮𝓷𝓮𝓼𝓼.” - Margaret Hamburg 🧬 Variability in drug response has long been observed in clinical practice, where some patients benefit significantly from a medication while others experience minimal effects or adverse reactions. Pharmacogenomics seeks to explain these differences at the genetic level, thereby supporting the broader goal of personalized medicine.           🔹 At the core of pharmacogenomics is the understanding that genetic variations, particularly single nucleotide polymorphisms (SNPs), can affect how drugs are absorbed, distributed, metabolized, and excreted. Enzymes involved in drug metabolism, especially those belonging to the cytochrome P450 family, exhibit genetic variability that can lead to differences in drug efficacy & toxicity.      ...