Abubakar Abubakar

“𝓜𝓮𝓽𝓱𝔂𝓵𝓪𝓽𝓲𝓸𝓷 𝓲𝓼 𝓪 𝓵𝓪𝓷𝓰𝓾𝓪𝓰𝓮 𝓬𝓮𝓵𝓵𝓼 𝓾𝓼𝓮 𝓽𝓸 𝓻𝓮𝓶𝓫𝓮𝓻 𝔀𝓱𝓸 𝓽𝓱𝓮𝔂 𝓪𝓻𝓮.” - Prof. Anne Ferguson-Smith 🧬 DNA methylation is a fundamental epigenetic mechanism that regulates gene expression without altering the DNA sequence itself. By adding methyl groups to cytosine residues, particularly within "CpG" regions, cells can selectively activate or silence genes, preserving cellular identity, developmental programming, and genomic stability.            🔹 This process is mediated by DNA methyltransferases (DNMTs), which establish and maintain methylation patterns across cell divisions. In promoter regions, hypermethylation often suppresses transcription, whereas hypomethylation is generally associated with gene activation. These highly coordinated patterns form part of broader epigenetic landscapes; dynamic networks that include histone modifications, chromatin remodeling, and non-coding RNAs...