DECODING LONG COVID: A BIOCHEMICAL PERSPECTIVE 🧠
🧬 In the ever-evolving landscape of post-pandemic health, a new opinion article by Dr. Carla P. Rus in Frontiers in Neurology (2025) offers a compelling dive into the biochemical roots of Long COVID, or Post-COVID Syndrome (PCS). Drawing from neuropsychiatry and biochemistry, the article explores how serotonin depletion and kynurenine pathway disruption could underlie the lingering symptoms so many continue to face.
🔹 At the heart of the discussion lies tryptophan; a vital amino acid that fuels both serotonin and kynurenine production. The paper suggests that malabsorption of tryptophan, heightened monoamine oxidase (MAO) activity, and gut-brain axis alterations may explain why patients with PCS experience brain fog, fatigue, anxiety, and dysautonomia.
🔹 Dr. Carla P. Rus proposes that these insights aren't just theoretical; they open the door for biomarker discovery and targeted treatments that could finally bring relief to millions grappling with Long COVID’s shadow.
🔹 This essay-style contribution stands as a call to the medical community: dig deeper, think broader, and connect the dots between biochemistry, immunity, and neuropsychiatric health.
🔗 Read it here: https://lnkd.in/dxK_cjKc
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