DECODING LONG COVID: A BIOCHEMICAL PERSPECTIVE π§
𧬠In the ever-evolving landscape of post-pandemic health, a new opinion article by Dr. Carla P. Rus in Frontiers in Neurology (2025) offers a compelling dive into the biochemical roots of Long COVID, or Post-COVID Syndrome (PCS). Drawing from neuropsychiatry and biochemistry, the article explores how serotonin depletion and kynurenine pathway disruption could underlie the lingering symptoms so many continue to face.
πΉ At the heart of the discussion lies tryptophan; a vital amino acid that fuels both serotonin and kynurenine production. The paper suggests that malabsorption of tryptophan, heightened monoamine oxidase (MAO) activity, and gut-brain axis alterations may explain why patients with PCS experience brain fog, fatigue, anxiety, and dysautonomia.
πΉ Dr. Carla P. Rus proposes that these insights aren't just theoretical; they open the door for biomarker discovery and targeted treatments that could finally bring relief to millions grappling with Long COVID’s shadow.
πΉ This essay-style contribution stands as a call to the medical community: dig deeper, think broader, and connect the dots between biochemistry, immunity, and neuropsychiatric health.
π Read it here: https://lnkd.in/dxK_cjKc
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