Today's blog is about an experience I had while visiting a religious site on the outskirts of town. As I was leaving, a lady approached me, asking for a donation. Unfortunately, I wasn’t carrying any cash at the time, so I asked her, "Do you use UPI by any chance?" She burst into laughter 😄, smiling at my unexpected question. The lesson here is that we should always be prepared with alternatives, as they might be a way to help others. At the very least, I managed to put a smile on her face, which made the encounter worthwhile 😊
"𝔓𝔯𝔦𝔪𝔢 𝔢𝔡𝔦𝔱𝔦𝔫𝔤, 𝔴𝔥𝔦𝔠𝔥 𝔠𝔞𝔫 𝔰𝔢𝔞𝔯𝔠𝔥-𝔞𝔫𝔡-𝔯𝔢𝔭𝔩𝔞𝔠𝔢 𝔇𝔑𝔄 𝔰𝔢𝔮𝔲𝔢𝔫𝔠𝔢𝔰 𝔴𝔦𝔱𝔥𝔬𝔲𝔱 𝔠𝔞𝔲𝔰𝔦𝔫𝔤 𝔡𝔬𝔲𝔟𝔩𝔢-𝔰𝔱𝔯𝔞𝔫𝔡 𝔟𝔯𝔢𝔞𝔨𝔰, 𝔬𝔣𝔣𝔢𝔯𝔰 𝔞 𝔪𝔬𝔯𝔢 𝔭𝔯𝔢𝔠𝔦𝔰𝔢 𝔞𝔫𝔡 𝔳𝔢𝔯𝔰𝔞𝔱𝔦𝔩𝔢 𝔱𝔬𝔬𝔩 𝔣𝔬𝔯 𝔤𝔢𝔫𝔬𝔪𝔢 𝔢𝔡𝔦𝔱𝔦𝔫𝔤." — Dr. Andrew Anzalone 🧬 Base editing and prime editing are revolutionary genome editing technologies that offer precise modifications to DNA sequences. Understanding their mechanisms and exploring their potential applications can lead to significant advancements in various fields. 🔹 Base editing involves the direct conversion of one DNA base to another without creating double-stranded breaks. This process relies on the fusion of a DNA-modifying enzyme and a programmable RNA-guided nuclease, such as CRISPR-Cas9. The enzyme catalyzes the chemical conversion of a specific base, resulting in targeted genetic alterations. For example, cytidine deamin...